A 40-year-old man is referred to the endocrine clinic with generalized body aches, visual defects and infrequent headache. He also observed mild disfigurement of his face. On examination, he has high blood pressure, frontal bossing, mandibular enlargement and enlarged hands What is the screening test that guides you to your provisional diagnosis of this man?
سؤال مجاني 1 من 10 اليوم · اشترك وكمّل بدون حد
اعرض الإجابة
الإجابة والشرح
ادخل لحسابك عشان نحفظ إجاباتك ونوريك أخطاءك.
الإجابة: D. Insulin like growth factor type 1 (IGF-1)
Frontal bossing, mandibular enlargement, large hands and hypertension suggest acromegaly; the screening test is serum IGF-1, the best single test. OGTT confirms afterwards; random GH is not useful because GH fluctuates widely; skull X-ray is not diagnostic.
ليش كل خيار صح أو غلط
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B
ليش غلط
The OGTT is the confirmatory test (GH not suppressed = acromegaly), done after an elevated IGF-1 - the most specific test, not the screening test.
✓ Pituitary disorder.pdf · p. 9 -
D
ليش صح
Serum IGF-1 is the best single test for acromegaly; if elevated, acromegaly is suspected and an OGTT follows.
✓ Pituitary disorder.pdf · p. 9 -
E
ليش غلط
The best single test is the IGF-1; a random GH level is not useful because GH fluctuates widely physiologically.
✓ Pituitary disorder.pdf · p. 9
- المصدر
- Pituitary disorder.pdf · p. 9
Pituitary summary.pdf · p. 2 - المحاضرة
- Pituitary Disorders · Endocrinology · Module B
- ظهر في
- Endo bank