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رجوع لأسئلة Cushing's Syndrome 7 / 16
B-472 مطابق للمصدر

Patient with Cushing syndrome symptoms Urine cortisol= normal. DEHA= low. ACTH= low What is the cause of his condition?

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الإجابة والشرح

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الإجابة: E. exogenous cortisol

✓ مطابق للمصدر Adrenal disorders (2).pdf · p. 7

Cushingoid features with low ACTH are ACTH-independent (adrenal tumour or exogenous steroids). Low DHEA shows suppressed adrenal androgens, and a normal urinary cortisol argues against an adrenal adenoma/carcinoma, which would make urinary free cortisol high. Cushing disease and ectopic ACTH both have high ACTH.

ليش كل خيار صح أو غلط

  • A ليش غلط

    Adrenal adenomas are ACTH-independent tumours that produce excess cortisol themselves, which does not fit the normal urine cortisol seen here.

    ✓ Adrenal summary.pdf · p. 1
  • B ليش غلط

    Adrenal carcinomas are ACTH-independent tumours that produce excess cortisol themselves, which does not fit the normal urine cortisol seen here.

    ✓ Adrenal summary.pdf · p. 1
  • C ليش غلط

    Cushing disease is an ACTH-secreting pituitary adenoma, so ACTH would be raised; here ACTH is low.

    ✓ Adrenal disorders (2).pdf · p. 7
  • D ليش غلط

    Ectopic ACTH syndrome is an ACTH-secreting tumour outside the pituitary driving cortisol, so ACTH would be raised; here ACTH is low.

    ✓ Adrenal disorders (2).pdf · p. 7
  • E ليش صح

    Exogenous steroids suppress adrenal androgen production (low DHEA) while causing Cushingoid features; it is also the most common cause of hypercortisolism.

    ✓ Adrenal disorders (2).pdf · p. 7
المصدر
Adrenal disorders (2).pdf · p. 7
Adrenal gland disorders.pdf · p. 1
المحاضرة
Cushing's Syndrome · Endocrinology · Module B
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