A 25-year-old patient with sickle cell disease with no past history of crisis or hospitalization complaining of fatigue and no other symptoms. hg 8.5, elevated reticulocytes. What is the preventative method to reduce risk of stroke?
سؤال مجاني 1 من 10 اليوم · اشترك وكمّل بدون حد
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الإجابة والشرح
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الإجابة: C. Hydroxyurea
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Step Up To Medicine 6th, 2024 (Anemias).pdf · p. 24
This is an adult with symptomatic SCD (fatigue, Hb 8.5). The sources indicate hydroxyurea for adults with severe/symptomatic sickle cell disease; it raises HbF and reduces vaso-occlusive events.
- Annual transcranial Doppler is a screening tool for children aged 2–16 only, not a 25-year-old.
- Chronic transfusion is started only after an abnormal Doppler (children) or as secondary prophylaxis after a stroke.
- Penicillin prophylaxis prevents infection (children <5), not stroke.
Note: the sources do not state outright that hydroxyurea prevents stroke in adults; C is the best-supported option.
- المصدر
- Step Up To Medicine 6th, 2024 (Anemias).pdf · p. 24
Hematology🩸.pdf · p. 21 - المحاضرة
- Haemoglobinopathies (SCD, Thalassaemia) · Hematology · Module C
- ظهر في
- MED42 ♂ EOM C