A 24-year-old man has a swollen right calf for 1 day. He had a deep vein thrombosis in the opposite leg when he was 17 years old, for which he took Warfarin for 3 months. His father also had deep vein thrombosis, but he is currently in good health. Examination shows a tender, swollen, right calf. Doppler studies confirm a diagnosis of thrombosis. Which of the following is the most likely risk factor for hypercoagulation patient?
سؤال مجاني 1 من 10 اليوم · اشترك وكمّل بدون حد
اعرض الإجابة
الإجابة والشرح
ادخل لحسابك عشان نحفظ إجاباتك ونوريك أخطاءك.
الإجابة: A. Factor V Leiden mutation
Young age, recurrent DVT and a positive family history point to an inherited thrombophilia, and factor V Leiden is the most common hereditary hypercoagulable disorder. Antiphospholipid syndrome is acquired/autoimmune (no family history pattern); nephrotic syndrome, occult malignancy and immobility do not fit a healthy 24-year-old with familial clots.
ليش كل خيار صح أو غلط
-
A
ليش صح
Factor V mutation is an inherited cause of hypercoagulability, and recurrent unprovoked VTE with a family history should make you think of one.
✓ UQU VTE 3.pdf · p. 7 -
B
ليش غلط
Antiphospholipid syndrome is listed as an acquired cause of hypercoagulability (antibody-mediated), whereas this young man's picture fits an inherited cause.
✓ 12• Venous Thromboembolism [Notes].pdf · p. 2 -
C
ليش غلط
Nephrotic syndrome is an acquired cause (antithrombin III is lost in the urine); a young man with a family history points to an inherited cause.
✓ 12• Venous Thromboembolism [Notes].pdf · p. 2 -
D
ليش غلط
Malignancy (e.g. lung or pancreatic cancer) is an acquired cause of increased thrombin formation, not an explanation for recurrent familial DVT in a 24-year-old.
✓ 12• Venous Thromboembolism [Notes].pdf · p. 2 -
E
ليش غلط
Prolonged immobilization is a stasis risk factor (slow blood flow in deep veins), not a hypercoagulable state.
✓ 12• Venous Thromboembolism [Notes].pdf · p. 2
- المصدر
- UQU VTE 3.pdf · p. 7
Step Up To Medicine 6th, 2024 (Bleeding disorders).pdf · p. 9 - المحاضرة
- Venous Thromboembolism · Pulmonology · Module B
- ظهر في
- Respi bank