A 45-year-old man has severe chest pain on mild to moderate exertion. The cardiologist prescribes oral organic nitrates and the diltiazem to be used concurrently for treatment of this type of angina Which best explains beneficial effects of the combination in this condition?
سؤال مجاني 1 من 10 اليوم · اشترك وكمّل بدون حد
اعرض الإجابة
الإجابة والشرح
ادخل لحسابك عشان نحفظ إجاباتك ونوريك أخطاءك.
الإجابة: C. Nitrates increase coronary flow while diltiazem reduce cardiac work
Nitrates dilate veins and arteries and increase myocardial O2 supply through coronary vasodilation. Diltiazem (non-DHP CCB) reduces heart rate, contractility and cardiac demand (cardiac work). Together they improve both supply and demand. Option D reverses the roles: nitrates mainly reduce preload, and diltiazem does not mainly act on preload.
ليش كل خيار صح أو غلط
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A
ليش غلط
Backwards: nitrates increase myocardial oxygen supply through coronary vasodilation, and diltiazem decreases (not enhances) cardiac activity and work.
✓ CARDIOLOGY- ISCHEMIC HEART DISEASES (IHDs).pdf · p. 5 -
B
ليش غلط
Nitrates do lower demand, but diltiazem does not act by reducing coronary flow: it lowers cardiac work (heart rate, contractility), while nitrates add supply through coronary vasodilation.
✓ CARDIOLOGY- ISCHEMIC HEART DISEASES (IHDs).pdf · p. 5 -
C
ليش صح
Nitrates raise myocardial O2 supply via coronary vasodilation, and diltiazem (non-DHP CCB) lowers heart rate, contractility and demand: supply up, demand down.
✓ CARDIOLOGY- ISCHEMIC HEART DISEASES (IHDs).pdf · p. 5 -
D
ليش غلط
Nitrates lower both preload and afterload, and diltiazem acts by reducing cardiac activity, HR and contractility rather than mainly lowering preload.
✓ CARDIOLOGY- ISCHEMIC HEART DISEASES (IHDs).pdf · p. 5
- المصدر
- CARDIOLOGY- ISCHEMIC HEART DISEASES (IHDs).pdf · p. 5
- المحاضرة
- Ischemic Heart Disease · Cardiology · Module B
- ظهر في
- Cardio bank