A 54 year old man has a 3 hour history of chest pain and dyspnea. He is 1 week post colectomy for colon cancer. On examination, temperature 37.5 C, BP 110/60 mmHg, HR 130/min, and RR 24/min. O2 sat is 88% on room air and 94% on oxygen, 4 L/min, cardiac examination shows tachycardia. Breath sounds are normal. Serum creatinine concentration is 3 mg/dl. CT pulmonary angiography shows left sided pulmonary embolism. Which of the following is the most appropriate immediate treatment?
سؤال مجاني 10 من 10 اليوم · اشترك وكمّل بدون حد
اعرض الإجابة
الإجابة والشرح
ادخل لحسابك عشان نحفظ إجاباتك ونوريك أخطاءك.
الإجابة: C. IV unfractionated heparin
This post-operative PE patient has significant renal impairment (creatinine 3 mg/dL) and a recent operation. IV unfractionated heparin needs no renal dose adjustment, is given as an IV infusion for therapeutic dosing, and has a short half-life that protamine can reverse if bleeding occurs. Fondaparinux is not recommended when CrCl <30, LMWH is cleared by the kidneys, and subcutaneous UFH is the prophylactic route, not treatment.
- المصدر
- Year4C- Anticoagulants🍓.pdf · p. 9
Year4C- Anticoagulants🍓.pdf · p. 11
Step Up To Medicine 6th, 2024 (anticoagulation).pdf · p. 1 - المحاضرة
- Anticoagulation · Hematology · Module C
- ظهر في
- Hema bank