A 49-year-old male schoolteacher presents with nausea and fatigability. He has right upper quadrant abdominal pain for 10 days duration. He has right chronic frozen shoulder and rotator cuff tendonitis. He takes pain medications regularly. He is found to be jaundiced as well. His initial laboratory findings are as follows: ALT 1680 U/L (normal range 7-55 U/L) AST 1988 U/L (normal range 8-48 U/L) Alkaline phosphatase 720 U/L (normal range 45-115 U/L) GGT 377 U/L (normal range 9-48 U/L) Which of the following represents the most likely etiology for this extreme elevation in liver enzymes?