A 50-year-old man with a history of non-valvular atrial fibrillation was diagnosed with a right leg deep vein thrombosis (DVT) one week ago. He underwent knee replacement surgery two weeks ago. He has poor compliance with medication and does not get frequent lab tests. He has no bleeding symptoms. His laboratory results show: Creatinine Clearance (CrCl): 25 mL/min. What is the best anticoagulant option for his condition?