A 50-year-old man with a history of non-valvular atrial fibrillation was diagnosed with a right leg deep vein thrombosis (DVT) one week ago. He underwent knee replacement surgery two weeks ago. He has poor compliance with medication and does not get frequent lab tests. He has no bleeding symptoms. His laboratory results show: Creatinine Clearance (CrCl): 25 mL/min. What is the best anticoagulant option for his condition?
سؤال مجاني 1 من 10 اليوم · اشترك وكمّل بدون حد
اعرض الإجابة
الإجابة والشرح
ادخل لحسابك عشان نحفظ إجاباتك ونوريك أخطاءك.
الإجابة: C. Apixaban
Here renal function decides: CrCl 25 mL/min. The patient also needs an oral agent with no lab monitoring, covering both AF and DVT.
- Apixaban is usable down to CrCl >15 mL/min.
- Rivaroxaban and dabigatran require CrCl >30.
- Fondaparinux is not recommended when CrCl <30 and is injectable.
ليش كل خيار صح أو غلط
-
A
ليش غلط
Fondaparinux is injectable and not recommended when CrCl is below 30 mL/min; this patient's CrCl is 25.
✓ Year4C- Anticoagulants🍓.pdf · p. 11 -
B
ليش غلط
Rivaroxaban requires CrCl >30 mL/min; this patient's CrCl is 25.
✓ Year4C- Anticoagulants🍓.pdf · p. 20 -
C
ليش صح
Oral factor Xa inhibitors need CrCl >30 mL/min, but apixaban only needs CrCl >15 mL/min, so it fits a CrCl of 25.
✓ Year4C- Anticoagulants🍓.pdf · p. 20 -
D
ليش غلط
Dabigatran requires CrCl >30 mL/min; this patient's CrCl is 25.
✓ Year4C- Anticoagulants🍓.pdf · p. 19
- المصدر
- Year4C- Anticoagulants🍓.pdf · p. 20
Year4C- Anticoagulants🍓.pdf · p. 19
Year4C- Anticoagulants🍓.pdf · p. 11 - المحاضرة
- Anticoagulation · Hematology · Module C
- ظهر في
- MED42 ♂ EOM C