Easy bruising and prolonged bleeding in a young man whose maternal uncle is affected suggests X-linked inheritance. A prolonged aPTT with normal PT means an intrinsic-pathway factor problem, and correction on mixing means factor deficiency rather than an inhibitor. Together these fit haemophilia A (factor VIII deficiency).

• vWD is autosomal and typically presents with mucocutaneous bleeding.
• Factor VII deficiency prolongs the PT, not the aPTT.
• Antiphospholipid antibodies (lupus anticoagulant) do not correct on mixing.