A 28-year-old patient with sickle cell anemia has been experiencing hand and leg pain, along with nausea and vomiting. He is dehydrated. Lab results show low hemoglobin and an elevated reticulocyte count. What is the most likely diagnosis?
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الإجابة: A. Vaso-occlusive crisis
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Hematology🩸.pdf · p. 19
Acute bone pain in the hands and legs after a trigger such as dehydration is a vaso-occlusive (pain) crisis: sickled cells obstruct the microcirculation and cause ischaemia. Low Hb with a high reticulocyte count is the usual chronic haemolytic baseline in SCD.
- An aplastic crisis would show a low reticulocyte count (e.g. parvovirus B19).
- Splenic sequestration presents with an enlarging spleen and hypovolaemic shock, not limb pain.
- المصدر
- Hematology🩸.pdf · p. 19
Step Up To Medicine 6th, 2024 (Anemias).pdf · p. 22 - المحاضرة
- Haemoglobinopathies (SCD, Thalassaemia) · Hematology · Module C
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- MED42 Compre C