A 65-year-old patient complaining of slow movement, difficulty initiating movement, and rigid limbs, his wife said that he has tremors but they disappear when reaching for something. On physical examination patient has bradykinesia, cogwheel rigidity, and resting tremors. What is the neurotransmitter involved in this condition?
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الإجابة: C. Dopamine
Bradykinesia, cogwheel rigidity and a resting tremor that disappears on movement = Parkinson disease, caused by progressive loss of dopaminergic neurons in the substantia nigra. Acetylcholine becomes relatively unopposed (hence anticholinergic therapy), but the deficient neurotransmitter is dopamine.
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A
ليش غلط
In Parkinson disease the cholinergic system operates unopposed, so acetylcholine is relatively excess; the compromised neurotransmitter is dopamine.
✓ Step Up To Medicine 6th Edition 2024(MOVEMENT DISORDER).pdf · p. 2 -
C
ليش صح
Parkinson disease is a progressive depletion of dopaminergic neurons in the substantia nigra, causing resting tremor, bradykinesia and rigidity.
✓ Movement disorder.pdf · p. 3
- المصدر
- Movement disorder.pdf · p. 3
Step Up To Medicine 6th Edition 2024(MOVEMENT DISORDER).pdf · p. 2 - المحاضرة
- Movement Disorders · Neurology · Module C
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- MED42 Compre C