A 37-year-old female presents to your department complaining of nausea and vomiting for the last 3 days. She has also been having headaches. Physical examination is only remarkable for abdominal distension and BP 165/100 mm Hg. Her BP has been high for the last 3 months despite treatment with amlodipine that was started at 5 mg once a day and was later increased to 10 mg once a day. Lab work reveals: Creatinine: 80 umol/L (N 50-90 umol/L) Chloride: 96 mmol/L (N 98-106 mmol/L) Bicarbonate: 31 mmol/L (N 24-30 mmol/L) Glucose: 5 mmol/L (N 4-11 mmol/L) Potassium test: 2.7 mmol/L (N 3.5-5.0 mmol/L) Sodium: 148 mmol/L (N 135-145 mmol/L) What is the most likely diagnosis?
سؤال مجاني 8 من 10 اليوم · اشترك وكمّل بدون حد
اعرض الإجابة
الإجابة والشرح
ادخل لحسابك عشان نحفظ إجاباتك ونوريك أخطاءك.
الإجابة: B. Conn's syndrome ( primary hyperaldosteronism)
Resistant hypertension + hypokalaemia (K⁺ 2.7) + metabolic alkalosis (HCO₃⁻ 31) + high-normal/raised Na⁺ is the picture of mineralocorticoid excess, i.e. primary hyperaldosteronism (Conn syndrome). Confirm with low renin and high aldosterone.
- Addison disease (D) causes hyponatraemia, hyperkalaemia and hypotension.
- Pheochromocytoma (C) gives paroxysmal hypertension without this electrolyte pattern.
- Cushing (A) would show cushingoid features and usually hyperglycaemia.
- المصدر
- Hypokalemia Davidson.pdf · p. 1
Step_Up_To_Medicine_6th,_2024_Electrolytes_Na,K_Imbalance.pdf · p. 10
RENAL-04 Potassium Disorders [Notes].pdf · p. 8 - المحاضرة
- Electrolytes (Na & K) · Nephrology · Module C
- ظهر في
- MED43 ♂ Quiz C