A patient with pulmonary TB is prescribed rifampicin. What is its mechanism of action?
سؤال مجاني 1 من 10 اليوم · اشترك وكمّل بدون حد
اعرض الإجابة
الإجابة والشرح
ادخل لحسابك عشان نحفظ إجاباتك ونوريك أخطاءك.
الإجابة: B. Inhibits DNA-dependent RNA polymerase
Rifampicin inhibits bacterial RNA synthesis by blocking (DNA-dependent) RNA polymerase. Cell-wall inhibition is the mechanism of isoniazid (mycolic acid synthesis) and ethambutol. DNA polymerase and protein synthesis are not rifampicin's targets.
ليش كل خيار صح أو غلط
-
A
ليش غلط
The target of rifampin is bacterial RNA polymerase (it blocks RNA synthesis), not DNA polymerase.
✓ Step Up To Medicine 6th Edition 2024 (TB and its treatment).pdf · p. 6 -
B
ليش صح
Rifampin inhibits bacterial RNA synthesis by blocking RNA polymerase.
✓ Step Up To Medicine 6th Edition 2024 (TB and its treatment).pdf · p. 6 -
C
ليش غلط
Blocking protein synthesis is how drugs like clindamycin (50S subunit) work, not rifampin.
✓ Antibiotics Review - Razan.pdf · p. 29 -
D
ليش غلط
Cell-wall effects belong to other TB drugs: isoniazid blocks mycolic acid synthesis and ethambutol inhibits a cell wall component.
✓ Step Up To Medicine 6th Edition 2024 (TB and its treatment).pdf · p. 6
- المصدر
- Step Up To Medicine 6th Edition 2024 (TB and its treatment).pdf · p. 6
- المحاضرة
- Tuberculosis · Pulmonology · Module B
- ظهر في
- MED41 ♀ EOM B