A 48-year-old male patient with hypertension and type 2 diabetes came to your clinic for intermittent right-hand numbness. He was found to have carpal tunnel syndrome caused by acromegaly. He asks you "what is the mechanism of carpal tunnel syndrome in acromegaly patients?
سؤال مجاني 6 من 10 اليوم · اشترك وكمّل بدون حد
اعرض الإجابة
الإجابة والشرح
ادخل لحسابك عشان نحفظ إجاباتك ونوريك أخطاءك.
الإجابة: A. Growth hormone stimulates abnormal protein synthesis in the canal
In acromegaly, excess GH raises IGF-1, which drives overgrowth of bone, cartilage and soft tissue; the enlarged soft tissue of the hands/wrist compresses the median nerve, giving carpal tunnel syndrome. Of the options, only A (GH-driven tissue growth inside the canal) matches this mechanism.
- The old bank key (B, electrolyte disturbance) is not supported by any source; B12 deficiency and a primary nerve-conduction defect are not mechanisms in the notes.
ليش كل خيار صح أو غلط
-
A
ليش صح
Excess GH raises IGF-1, which drives skeletal and muscle growth; the resulting large hands and fingers carry an increased risk of carpal tunnel syndrome.
✓ 4• Pituitary Disorders [Notes].pdf · p. 4 -
B
ليش غلط
The source gives the mechanism as GH/IGF-1 driven overgrowth of tissue, not an electrolyte disturbance.
✓ Pituitary disorder.pdf · p. 8 -
C
ليش غلط
The source describes IGF-1-driven overgrowth of bone, cartilage and soft tissue, not a primary nerve-conduction effect of GH.
✓ Pituitary disorder.pdf · p. 8 -
D
ليش غلط
The notes attribute acromegaly symptoms to GH/IGF-1 cell overgrowth; vitamin B12 deficiency is not part of the mechanism.
✓ Pituitary disorder.pdf · p. 8
- المصدر
- Pituitary disorder.pdf · p. 8
4• Pituitary Disorders [Notes].pdf · p. 4 - المحاضرة
- Pituitary Disorders · Endocrinology · Module B
- ظهر في
- Endo bank