The cohort's pituitary sources do not cover pituitary metastasis or pituitary carcinoma, so the lung-cancer clue in the stem cannot be checked against them. They only say that non-secretory macroadenomas are the most common cause of hypopituitarism in adults, and that LH/FSH/GH are usually lost before TSH and ACTH. The old bank's answer of metastasis (C) fits the known primary tumour and the widespread loss of hormones, but no source here confirms it, and the original key was recorded as 'IDK'.