A 23-year-old woman has easy fatigability in early morning for the last 6 weeks and dizziness on standing. examination, HR 100bpm, BP supine 120/80mmHg and standing 90/65mmHg, with gum hyperpigmentation. Which of the following is the most appropriate test to be done?
سؤال مجاني 1 من 10 اليوم · اشترك وكمّل بدون حد
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الإجابة: B. ACTH stimulation test
Fatigue, orthostatic hypotension and gum hyperpigmentation point to primary adrenal insufficiency (Addison's). The ACTH (Synacthen/cosyntropin) stimulation test confirms it: cortisol fails to rise after exogenous ACTH. Dexamethasone suppression, 24-hour urinary free cortisol and late-night salivary cortisol are screening tests for cortisol excess (Cushing's), not deficiency.
ليش كل خيار صح أو غلط
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A
ليش غلط
The low-dose dexamethasone suppression test is one of the screening tests for Cushing syndrome (cortisol excess), not a test for adrenal insufficiency.
✓ 6• Cushing's Syndrome & Disease [Notes].pdf · p. 5 -
B
ليش صح
In suspected adrenal insufficiency, the short ACTH stimulation (Synacthen) test is the confirmatory test: cortisol fails to rise after exogenous ACTH.
✓ RT - Adrenal.pdf · p. 12 -
C
ليش غلط
24-hour urinary cortisol is one of the screening tests for Cushing syndrome (cortisol excess), not a test for adrenal insufficiency.
✓ 6• Cushing's Syndrome & Disease [Notes].pdf · p. 5 -
D
ليش غلط
Late-night salivary cortisol is one of the screening tests for Cushing syndrome (cortisol excess), not a test for adrenal insufficiency.
✓ 6• Cushing's Syndrome & Disease [Notes].pdf · p. 5
- المصدر
- RT - Adrenal.pdf · p. 12
Adrenal disorders (2).pdf · p. 5 - المحاضرة
- Adrenal Insufficiency · Endocrinology · Module B
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- Endo bank