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رجوع لأسئلة Diabetes Mellitus 49 / 60
B-442 مطابق للمصدر

Your colleague asked how can lisinopril slows the progression of diabetic nephropathy? The appropriate answer is:

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الإجابة والشرح

ادخل لحسابك عشان نحفظ إجاباتك ونوريك أخطاءك.

الإجابة: A. Lisinopril reduces glomerular hydrostatic pressure

✓ مطابق للمصدر 11• Diabetes Mellitus [Notes].pdf · p. 13

ACE inhibitors block angiotensin II-mediated efferent arteriolar constriction; efferent dilation lowers intraglomerular (hydrostatic) pressure, reducing hyperfiltration and albuminuria and slowing nephropathy. They decrease (not increase) aldosterone and do not act on tubular glucose handling (that is SGLT2 inhibitors).

ليش كل خيار صح أو غلط

  • A ليش صح

    ACE inhibitors dilate the efferent arteriole, which lowers glomerular pressure and so reduces the protein pushed into Bowman's capsule (albuminuria) in diabetic kidney disease.

    ✓ 11• Diabetes Mellitus [Notes].pdf · p. 13
  • B ليش غلط

    ACE inhibitors work by inhibiting the renin-angiotensin-aldosterone system, so aldosterone release falls; they do not increase aldosterone activity.

    ✓ Step Up To Medicine 6th (Hypertension).pdf · p. 5
  • C ليش غلط

    Lisinopril's kidney effect is dilation of the efferent arteriole of the glomerulus, which slows the progression of proteinuria; it is not described as raising renal arterial blood flow.

    ✓ Step Up To Medicine 6th, 2024 (CKD).pdf · p. 4
المصدر
11• Diabetes Mellitus [Notes].pdf · p. 13
Step Up To Medicine 6th, 2024 (CKD).pdf · p. 4
المحاضرة
Diabetes Mellitus · Endocrinology · Module B
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