A 30-year-old woman presents with confusion, sweating, hunger, and fatigue. Random blood sugar is 40 mg/dL. She has no history of diabetes mellitus, although her sister is an insulin-dependent diabetic. The patient has had several similar episodes over the past year. Before correcting her hypoglycemia, blood sample for serum insulin, C- peptide, and B-hydroxybutyrate are sent to the lab. Which of the following finding is the best suggestive of the diagnosis of insulinoma?
سؤال مجاني 1 من 10 اليوم · اشترك وكمّل بدون حد
اعرض الإجابة
الإجابة والشرح
ادخل لحسابك عشان نحفظ إجاباتك ونوريك أخطاءك.
الإجابة: B. High insulin, high C-peptide, and low B-hydroxybutyrate
An insulinoma is a β-cell tumour secreting endogenous insulin, and C-peptide is the marker of endogenous insulin secretion — so both insulin and C-peptide are high; the excess insulin suppresses ketogenesis, so β-hydroxybutyrate is low.
- High insulin with low C-peptide (options A, C, D) indicates exogenous insulin injection — relevant here because her sister is an insulin user.
ليش كل خيار صح أو غلط
-
A
ليش غلط
High insulin with low C-peptide means the insulin is exogenous (injected), because exogenous insulin does not contain C-peptide; her sister uses insulin.
✓ Step Up To Medicine 6th Edition 2024 (DM).pdf · p. 22 -
B
ليش صح
C-peptide marks endogenous insulin secretion. An insulinoma is a beta-cell tumour that makes its own insulin, so insulin and C-peptide are both high.
✓ Diabetes mellitus overall Copy.pdf · p. 6 -
C
ليش غلط
High insulin with low C-peptide indicates exogenous insulin rather than an insulinoma, since injected insulin contains no C-peptide.
✓ Step Up To Medicine 6th Edition 2024 (DM).pdf · p. 22 -
D
ليش غلط
High insulin with low C-peptide points to injected insulin (factitious hypoglycaemia), not an insulinoma.
✓ Step Up To Medicine 6th Edition 2024 (DM).pdf · p. 22
- المصدر
- Diabetes mellitus overall Copy.pdf · p. 6
Insulinoma.pdf · p. 1
Step Up To Medicine 6th Edition 2024 (DM).pdf · p. 22 - المحاضرة
- Hypoglycaemia · Endocrinology · Module B
- ظهر في
- Endo bank