A 52-year-old woman has T2DM, hypertension, dyslipidemia, and mild renal impairment with eGFR .. has been on diet control and metformin. On examination, her BMI is 33 with normal vital signs and mild limb edema. She has no evidence of retinopathy or peripheral neuropathy. Her HbA1c level is 8% Which of the following will be the best add-on hypoglycemic agent for this patient?
سؤال مجاني 10 من 10 اليوم · اشترك وكمّل بدون حد
اعرض الإجابة
الإجابة والشرح
ادخل لحسابك عشان نحفظ إجاباتك ونوريك أخطاءك.
الإجابة: B. SGLT-2 inhibitor
She is on metformin, has renal impairment, and is obese. When CKD (or heart failure) dominates, an SGLT-2 inhibitor is the preferred add-on: it protects the kidneys and causes weight loss. A thiazolidinedione causes weight gain and oedema (she already has limb oedema). Sulfonylureas and insulin cause weight gain and hypoglycaemia.
ليش كل خيار صح أو غلط
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A
ليش غلط
Insulin is the preferred second-line drug when HbA1c is above 8.5 despite metformin; hers is 8%.
✓ RT - DM.pdf · p. 9 -
B
ليش صح
When heart failure or CKD predominates, the slides prescribe a low dose of an SGLT2 inhibitor; she has renal impairment and oedema.
✓ RT - DM.pdf · p. 12 -
C
ليش غلط
Sulfonylureas are listed with weight gain and hypoglycaemia, a poor fit for an obese patient (BMI 33).
✓ RT - DM.pdf · p. 10 -
D
ليش غلط
Thiazolidinediones cause fluid retention and weight gain, which is a poor fit for a patient who already has limb oedema.
✓ Anti-diabetic.pdf · p. 5
- المصدر
- RT - DM.pdf · p. 12
11• Diabetes Mellitus [Notes].pdf · p. 10 - المحاضرة
- Diabetes Mellitus · Endocrinology · Module B
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- Endo bank