Office Q17. A 40-year-old man comes to the o%ce due to exertional dyspnea of 6 months' duration. He occasionally expectorates mucoid sputum. His father died of nonalcoholic liver cirrhosis. Vital signs are normal and breath sounds are decreased bilaterally. CT Chest showed bilateral lower lobe emphysema. Which of the following is the most likely diagnosis?
سؤال مجاني 1 من 10 اليوم · اشترك وكمّل بدون حد
اعرض الإجابة
الإجابة والشرح
ادخل لحسابك عشان نحفظ إجاباتك ونوريك أخطاءك.
الإجابة: A. Alpha-1 an trypsin deficiency
Emphysema at a young age (40), basal (lower-lobe) emphysema, and a family history of liver cirrhosis point to alpha-1 antitrypsin deficiency, which causes panacinar lower-lobe emphysema. Chronic bronchitis is a smoker's cough-and-sputum diagnosis. CF and aspergillosis do not cause basal emphysema with liver disease.
ليش كل خيار صح أو غلط
-
A
ليش صح
Onset before age 45 and basal (lower-lobe) emphysema are listed reasons to consider alpha-1 antitrypsin deficiency; the same list includes liver disease/cirrhosis, which fits his father's nonalcoholic cirrhosis.
✓ COPD.pdf · p. 3 -
B
ليش غلط
Chronic bronchitis needs cough and sputum for at least 3 consecutive months in each of 2 consecutive years; he has exertional dyspnea with only occasional sputum and basal emphysema on CT.
✓ COPD.pdf · p. 2 -
C
ليش غلط
Cystic fibrosis is a differential that presents with excessive cough and mucus production; it does not fit exertional dyspnea with occasional sputum and basal emphysema.
✓ Asthma & asthma exacerbation.pdf · p. 5
- المصدر
- COPD.pdf · p. 3
COPD.pdf · p. 5 - المحاضرة
- COPD · Pulmonology · Module B
- ظهر في
- Respi bank